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ONDANSETRON
(Zofran ODT)

Ondansetron Tablet

PACKAGED: 4 mg tablet

LOCATION: Intermediate Pouch

INDICATION:
For nausea or active vomiting

ADULT: 
4 mg SL

PEDI:
Ondansetron 4 mg PO if pt ≥ 12 y/o and wt is ≥ 40 kg.

Transport time should be considered prior to administration.

THERAPEUTIC ACTION:
Stimulation of 5-HT 3 receptors causes transmission of sensory signals to the vomiting center via vagal afferent fibers to induce vomiting.  By binding to 5-HT 3 receptors, Ondansetron blocks vomiting mediated by serotonin release.

CONTRAINDICATION:
Known hypersensitivity to Ondansetron

PRECAUTIONS AND SIDE EFFECTS:
During pregnancy it should only be used where clearly needed.
Sudden blindness of 2-3 minutes duration has occurred. It is suggested that the speed of delivery may contribute to the blindness.
Constipation, diarrhea, fever, headache.

REQUIRES MCP:
ADULT: No 
PEDI: No