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SODIUM THIOSULFATE

Sodium Thiosulfate

PACKAGED:  12.5 gm in 50 ml vial

LOCATION:  Not carried in drug bag, stored in regional caches

INDICATIONS:
Conscious patient with known or suspected Cyanide poisoning
Smoke Inhalation with suspected cyanide component
Cardiac Arrest from known or suspected Cyanide poisoning or smoke inhalation

ADULT: 
12.5 gm (50 ml) 25% solution slow IV

PEDI:
Children > 25 kg: 12.5 gm (50 ml) 25% solution slow IV
Children < 25 kg: 412.5 mg/kg (1.65 ml/kg) of 25% solution (max dose 12.5 g (50 ml))

THERAPEUTIC ACTION:
Accelerates detoxification of cyanide

CONTRAINDICATION:
None

PRECATIONS AND SIDE EFFECTS:
Possible hypotension

REQUIRES MCP:
ADULT: Yes, unless arrest situation      
PEDI: Yes, unless arrest situation