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ADENOSINE

Adenosine
Adenosine

PACKAGED: 6 mg (1 in drug bag) and 12 mg (2 in drug bag) prefilled syringes or vials

LOCATION: Main Compartment

INDICATION:
Stable PSVT

ADULT: 
6 mg rapid IV as quickly as possible
If not successful, may repeat 12 mg rapid IV.
If not successful, may repeat 12 mg rapid IV.
All doses of Adenosine are followed by 20 ml bolus of NS.
Go directly to 12 mg if patient with history of PSVT advises it takes 12 mg.  May repeat x one.

PEDI:
0.1 mg/kg rapid IV followed by 10 ml rapid saline flush. Max single dose 6 mg.
If unsuccessful, 0.2 mg/kg rapid IV followed by 10 ml rapid saline flush. Max single dose 12 mg. May repeat x one.

THERAPEUTIC ACTION:
Decreases electrical conduction through the AV node without causing negative inotropic effects 
Acts directly on SA node to decrease chronotropic activity

CONTRAINDICATIONS:
Second or third degree AV block or sick sinus syndrome 
Hypersensitivity to Adenosine

PRECAUTIONS AND SIDE EFFECTS:
Lightheadedness, paresthesia, headache, diaphoresis, palpitations, chest pain, hypotension, shortness of breath, transient periods of sinus bradycardia  sinus pause, or asystole, ventricular ectopy, nausea, metallic taste. May produce bronchoconstriction in patients with asthma and in patients with bronchopulmonary disease.

REQUIRES MCP:
ADULT: No  
PEDI: No