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epinephrine
(see also Epi-Pen - BLS Pouch)

Epi


PACKAGED:
1:10,000—l mg/10ml (6 in drug bag) 10 ml prefilled syringe
1:1,000—30 ml vial, 1 mg/ml
Auto-injector: Adult 0.3 mg

LOCATION: Main Compartment

INDICATIONS:
VF, pulseless VT, asystole, PEA
Asthma in severe distress
Anaphylaxis or allergic reaction in patients who remain hypotensive after fluid bolus

ADULT: 
VF, pulseless VT, asystole and PEA:
1 mg IV 1:10,000, repeat every 3-5 minutes

Asthma, anaphylaxis:
If ≥ 30 kg, give both Adult EpiPen and EpiPen Jr or Epi (1:1,000) 0.5 mg IM
May repeat in 5 minutes

Allergic Reaction, Anaphylaxis in patients who remain hypotensive after fluid bolus: 0.1 mg, 1:10,000, slow IV, every 3 minutes, up to 0.5 mg.

PEDI:
VF, PULSELESS VT, Asystole and PEA, Bradycardia:
0.01 mg/kg of 1:10,000 IV; repeat every 3-5 min.

Asthma, Anaphylaxis:
If < 15 kg, EpiPen Jr or Epi (1:1,000) 0.01 mg/kg IM (max 0.15 mg).
If ≥ 15 kg and < 30 kg, Adult EpiPen or Epi (1:1,000) 0.01 mg/kg IM (max 0.3 mg)
May repeat Epi (1:1,000) 0.01 mg/kg IM (max 0.5 mg) after 5 minutes.

THERAPEUTIC ACTION:
Directly stimulates alpha and beta adrenergic receptors in dose-related fashion; causes bronchodilation, vasoconstriction, and increased cardiac output.

CONTRAINDICATIONS:

PRECAUTIONS AND SIDE EFFECTS:
Headache, nausea, restlessness, weakness, dysrhythmias, including ventricular tachycardia and ventricular fibrillation, hypertension, precipitation of angina pectoris, tachycardia
May increase myocardial oxygen demand
Syncope has occurred following epinephrine administration to asthmatic children.

REQUIRES MCP:
ADULT: For arrest—No.
                For repeat in asthmas, anaphylaxis --Yes

PEDI: For arrest—No
            For repeat in asthmas, anaphylaxis —Yes